Hepatocarcinoma is a challenge in all aspects such as diagnosis, staging or selection of the best treatment for each patient. In a few disorders like this one and in all the phases of their attention, the collaboration of several specialties is necessary. Therefore, and with the double objective of updating the latest technical knowledge and highlighting the importance of multidisciplinary work, this conference is organized primarily for Hepatologists, Oncologists, Radiologists and Surgeons.
The day is organized by Dr. Javier Crespo García Chief of Digestive Service of H.U. Marqués de Valdecilla Dr. Fernando Rivera Herrero Head of the Oncology Service of H.U. Marqués de Valdecilla Dr. Juan Carlos Rodríguez Sanjuán Head of the General Surgery Service of the H.U. Marquis of Valdecilla Dr. Carlos López López. FEA, Oncology Service, H.U. Marquis of Valdecilla Dr. Carlos Rodríguez de Lope. FEA, Digestive Service, H.U. Marquis of Valdecilla.
Program of the Day: https://chcvaldecilla.es/programa/
Prior registration and written confirmation is essential to attend the meeting.
End of the online registration period: February 29
Registration: https://chcvaldecilla.es/inscripcion-hotel/
Free registration until the capacity is completed.
Headquartes of the day:
Dr. Gómez Durán Assembly Hall, Marqués de Valdecilla University Hospital
Accreditation in continued training:
In management with the Commission for Continuing Education of the Health Professions of Cantabria.
Hepatocarcinoma is a challenge in all aspects such as diagnosis, staging or selection of the best treatment for each patient. In a few disorders like this one and in all the phases of their attention, the collaboration of several specialties is necessary. Therefore, and with the double objective of updating the latest technical knowledge and […]
The article “Diagnostic value of Bone marrow core biopsy patterns in Lymphoplasmacytic Lymphoma / Waldeström Macroglobulinemia and description of its mutational profiles by targeted NGS” has recently been published in the international Journal of Clinical Pathology (FI 2,346, JCR).
This original manuscript describes the clinical relevance of the evaluation by multiparameter methods (morphology and histopathology, immunohistochemistry, flow cytometry and mutational study) of bone marrow biopsy for the accurate diagnosis of patients with lymphoplasmacytic B lymphoma / Waldestrom Macroglobulinemia and its distinction from the precursor phase of the disease called Monoclonal Gammopathy of IgM Uncertain Meaning.
In a novel way, the latest generation technology of directed sequencing of the exome is applied by Next Generation Sequencing to characterize the mutational profile of this lymphoid neoplasm using clinical samples.
The work has been developed in the IDIVAL Translational Hematopathology Laboratory, in collaboration with the HUMV Pathology and Hematology Department, the Valdecilla Biobank and the Center for Genomic Regulation of Barcelona.
Ref. Diagnostic value of Bone marrow core biopsy patterns in Lymphoplasmacytic Lymphoma/Waldeström Macroglobulinemia and description of its mutational profiles by targeted NGS. J Clin Pathol 2020 Jan 24 [Online ahead of print]. PMID: 31980558 DOI: 10.1136/jclinpath-2019-206282. Autores: Julia Garcia-Reyero, Nerea Martinez Magunacelaya, Sonia Gonzalez de Villambrosia, Angela Gomez Mediavilla, Marcela Urquieta Lam, Andres Insunza Gaminde, Raul Tonda, Sergi Beltran, Marta Gut, Ainara Gonzalez Pereña y Santiago Montes-Moreno.
The article “Diagnostic value of Bone marrow core biopsy patterns in Lymphoplasmacytic Lymphoma / Waldeström Macroglobulinemia and description of its mutational profiles by targeted NGS” has recently been published in the international Journal of Clinical Pathology (FI 2,346, JCR). This original manuscript describes the clinical relevance of the evaluation by multiparameter methods (morphology and histopathology, […]
The Leonardo Scholarships for Researchers and Cultural Creators granted by the BBVA Foundation are intended to directly support the work of researchers and cultural creators between 30 and 45 years of age who, being in the middle stages of their career, develop a markedly personal and innovative project in the corresponding area of specialization or activity in the following areas:
At least 55 scholarships will be awarded for the whole of the call, each with a maximum gross amount of 40,000 euros. The overall allocation of this call is set at 2,200,000 euros. The projects submitted will last between 12 and 18 months from the subscription of the scholarship acceptance commitment. The project object of the requested scholarship must be completed at the end of this period. If the project presented were to be developed in a university, a public research center, a private (non-profit) research center or a hospital, the applicant must be attached to it at the time of signing the acceptance commitment.
Deadline for submission of applications: from January 15, 2020 to March 18, 2020, at 7:00 p.m. Peninsular time.
More information about the call in the following link: https://www.redleonardo.es/becas/becas-leonardo-investigadores-creadores-culturales-2020/
The Leonardo Scholarships for Researchers and Cultural Creators granted by the BBVA Foundation are intended to directly support the work of researchers and cultural creators between 30 and 45 years of age who, being in the middle stages of their career, develop a markedly personal and innovative project in the corresponding area of specialization or […]
Next Thursday, February 27, the next conference of the fourth edition of the Santander Biomedical Lectures program organized by IDIVAL, the University of Cantabria and the IBBTEC given by Dr. Martin will be held with the title “MTBVAC a new vaccine against tuberculosis, from laboratory to clinical trials of efficacy in endemic countries ”.
Carlos Martín is Professor of Microbiology at the Faculty of Medicine of the University of Zaragoza and directs the Group of Genetics of Mycobacteria (TBVI), belonging to the CIBER of Respiratory Diseases of the Carlos III Health Institute. His work focuses on the research and development of new live vaccines against tuberculosis. Dr. Martín and his team have built and characterized the MTBVAC vaccine, now in clinical trials. He is currently working on various research projects funded by the European Union in tuberculosis collaborating with research groups in Europe, Africa and Latin America. He is a member of the Research & Innovation group of the Tuberculosis Vaccines Initiative (TBVI) http://www.tbvi.eu/ with more than 25 years of experience in mycobacterial genetics.
Dr. Martín trained at the Pasteur Institute in Paris, where he was a permanent researcher in the team of Professor Brigitte Gicquel, pioneer of genetic studies of tuberculosis. His previous research training focused on studies of resistance mechanisms with Professor Juan María García Lobo and transposition in bacteria with Professor Fernando de la Cruz in the Department of Biochemistry and Molecular Biology of the University of Cantabria.
He has published more than one hundred and fifty international publications cited more than 8,500 times in recent years (ResearcherID: A-7283-2008). Dr. Martin's research has been continually funded by the National and European Union Research Programs since the formation of his Research Group in 1992 (TBVI).
The conference is open to all the public of Santander who wants to participate. It will take place on Thursday, February 27 at the Marqués de Valdecilla University Hospital, in the Téllez Plasencia Hall (Hall 16) at 8.15 am in the morning.
Promoting a discussion forum on the current advances in biomedicine, the rapporteur will remain in our Community throughout the day of the session, to exchange experiences with members of the scientific and clinical community of Santander, and to visit the research centers of our community to meet interested scientists firsthand.
The speaker is invited by Dr. Alain Ocampo, Miguel Servet's contract at the Marqués de Valdecilla Research Institute (IDIVAL) in the group Epidemiology and Pathogenic and Molecular Mechanisms of Infectious Diseases and Clinical Microbiology. Those professionals who wish to have a meeting with the speaker during their visit can contact through the following e-mails: aocampo@idival.org or projects1@idival.org
Next Thursday, February 27, the next conference of the fourth edition of the Santander Biomedical Lectures program organized by IDIVAL, the University of Cantabria and the IBBTEC given by Dr. Martin will be held with the title “MTBVAC a new vaccine against tuberculosis, from laboratory to clinical trials of efficacy in endemic countries ”. Carlos […]
The User Care, Immunology and Radiodiagnostic Services of the Marqués de Valdecilla University Hospital have received the ISO 9001: 2015 accreditation, which certifies their commitment to quality and safety in the framework of continuous improvement to achieve the best health results.
With these three new accreditations, Valdecilla brings to 20 the number of services and units that have this quality certification, 18 in the hospital and two in the Valdecilla Health Research Institute Foundation (IDIVAL).
The Minister of Health, Miguel Rodríguez, has valued the obtaining of these accreditations, ensuring that they guarantee “that the highest quality standards that ISO standards establish are met and that allow us to continue growing the Valdecilla brand”. The Ministry of Health, has referred to the effort involved in achieving this accreditation and the obligations arising from its maintenance for all professionals. In this regard, he pointed out “that this is going to be the easiest part” because of the involvement and dedication that professionals contribute to their daily work.
The closing ceremony was attended together with the Minister of Health, the Managing Director of the Cantabrian Health Service, Celia Gómez; the managing director of Valdecilla, Rafael Tejido; the director of management of IDIVAL, Galo Peralta; and the head of the accrediting company DNV-GL, Mónica de Miguel.
Celia Gómez has congratulated the professionals “for the effort involved in being in the space of continuous improvement and on the path of excellence”, pointing out as a challenge to be better and make better the work and the quality of care provided to the patients. He also thanked the workers “make excellence your habit.”
For his part, Rafael Tejido has recognized and thanked the efforts of professionals to achieve these quality certifications, noting that they put Valdecilla on the path of excellence. For this reason, it has encouraged professionals to continue in this line of continuous improvement.
Finally, Galo Peralta has valued the effort and work that exist behind each accreditation, highlighting that “the IDIVAL is what it is, in large part, because of its commitment to quality”.
Share to improve
The ‘Quality and Benchmarking Day between Services and Units with ISO: sharing to improve’ has been aimed at sharing and disseminating the experience and best practices of the units and services that already have ISO accreditation.
Structured in four round tables, within the context, strategy and communication area, the experiences of user care, pathology, lung transplantation, pediatric urgency and innovation (framed in the IDIVAL) have been presented.
The risk and opportunity management table has been composed of endoscopies, sterilization, immunology, the clinical trials unit and the IDIVAL biobank.
Pharmacy, microbiology, liver transplantation, the hyperbaric therapy unit and renal and pancreatic transplantation, have been part of the table focused on the patient's vision.
The last table, related to measurement, analysis and continuous improvement, has been constituted by hemotherapy, intensive medicine, radiodiagnosis and transplant coordination.
The User Care, Immunology and Radiodiagnostic Services of the Marqués de Valdecilla University Hospital have received the ISO 9001: 2015 accreditation, which certifies their commitment to quality and safety in the framework of continuous improvement to achieve the best health results. With these three new accreditations, Valdecilla brings to 20 the number of services and […]
The study “Nonpharmacological, nonsurgical treatments for freezing of gait in Parkinson's disease: A systematic review” published in the journal Movement Disorders, has been led by Manuel Delgado, Neurologist of the Sierrallana Hospital and researcher of the Area of Psychiatry of IDIVAL and has had the participation of other experts in disorders of the movement of the HUMV and the University Bio-Medical Campus of Rome.
The work consists of a systematic review of the existing literature, according to international guidelines, which tries to answer a simple question: what non-pharmacological treatments exist to treat gait blockages in Parkinson's disease and what effectiveness do they have Gait blockages are common in Parkinson's disease, especially in advanced cases, and have an important impact on the patient's quality of life. They consist of a momentary inability to walk despite having the intention of doing so. In many cases they are difficult to treat and respond poorly to medications so, in recent years, multiple studies have investigated the use of non-pharmacological therapies for their management, such as physiotherapy, cognitive stimulation, magnetic transcranial stimulation or the use of glasses of augmented reality.
To date, this issue had not been systematically reviewed. In addition to assessing the quality of studies published so far, this review offers a classification of the various existing treatments based on their mechanism of action. This pathophysiological view of the various approaches serves as an integrating point of what has been done so far and as a starting point for future studies. Along these lines, Dr. Delgado leads an IDIVAL-funded project, in which an augmented reality system reinforced with mechanical feedback has been developed, the effectiveness of which will be explored soon in a group of patients with Parkinson's disease.
The study “Nonpharmacological, nonsurgical treatments for freezing of gait in Parkinson's disease: A systematic review” published in the journal Movement Disorders, has been led by Manuel Delgado, Neurologist of the Sierrallana Hospital and researcher of the Area of Psychiatry of IDIVAL and has had the participation of other experts in disorders of the movement of […]
On February 14, the Call for Official Selection of the Scientific Director of the Marqués de Valdecilla Research Institute Foundation (IDIVAL) has been published in the Official Gazette of Cantabria. The functions of the Scientific Director are contemplated in article 35 of the founding Statutes (link to the Statutes of IDIVAL)
Applicants who meet the following requirements may participate in this call:
a) To have the status of permanent staff in active duty, as fixed statutory staff or as a holder of a linked position as provided in article 105.1 of Law 14/1986, of April 25, General of Health.
b) Provide services at the “Marqués de Valdecilla” University Hospital.
c) Be in possession of the University degree of Doctor.
d) Have at least one research project as a Principal Investigator funded through a national or international competitive call in the last five years.
Submission of applications will end on February 24, 2020.
After the deadline for submitting applications, the Management Department will verify compliance with the requirements by the candidates and will forward the list of admitted to the President of the Board.
The President of the Board of Trustees may conduct an interview with applicants who meet the participation requirements that allow them to deduct their skills for the requested job.
This call will be resolved by the system of free designation by resolution of the Board, at the motivated proposal of the President and may be declared void by reasoned agreement when no suitable applicants concur for the performance of the same.
Official Bulletin of Cantabria (link)
Correction of calls errors
On February 14, the Call for Official Selection of the Scientific Director of the Marqués de Valdecilla Research Institute Foundation (IDIVAL) has been published in the Official Gazette of Cantabria. The functions of the Scientific Director are contemplated in article 35 of the founding Statutes (link to the Statutes of IDIVAL) Applicants who meet the […]
Proposal for a provisional resolution to grant the 2019 call for grants for predoctoral contracts of the Research Personnel Program in Predoctoral Training in the area of biomedicine, biotechnology and health sciences, published by resolution of the Director of Management of the Marquis Research Institute of Valdecilla (IDIVAL) and the Vice Chancellor for Research and Knowledge Transfer of the University of Cantabria (BOC 09-30-2019).
The first three applicants of Annex I with the best final score for each field of research will be considered selected candidates.
Applicants will have a period of 10 business days, counting from the day following the publication of this motion for a resolution on the Internet address: https://web.unican.es/investigacion/convocatorias/detalle?c=315&a=246 to formulate the allegations they deem appropriate.
Resolution Annex
More information on the following link
Proposal for a provisional resolution to grant the 2019 call for grants for predoctoral contracts of the Research Personnel Program in Predoctoral Training in the area of biomedicine, biotechnology and health sciences, published by resolution of the Director of Management of the Marquis Research Institute of Valdecilla (IDIVAL) and the Vice Chancellor for Research and […]
The CaixaImpulse Call is intended for the financing of projects focused on the valuation and commercialization of the protected or susceptible assets protected by the investigation. Projects must be related to the fields of life sciences, medical sciences and health sciences, specifically in the following fields:
Life sciences: biomathematics, cell biology, human biology, biochemistry and molecular biology, human physiology, genetics, immunology, microbiology and neurosciences.
Medicine and health sciences: clinical sciences, epidemiology, forensic medicine, occupational medicine, internal medicine, nutrition sciences, pathological anatomy, pharmacodynamics, pharmacology, preventive medicine, psychiatry, public health, surgery and toxicology.
Projects may or may not be in the process of obtaining a patent or a utility model. If this is not the case, asset protection must be included in the valuation plan and budget, and the patent or utility model must be requested before the valuation contract is signed.
The program will offer an expert accompaniment program, an economic contribution and the necessary training to carry out the business plan.
Amount: Maximum € 100,000.
The deadline of this first phase is March 16, 2020.
More information about the call on the following link: https://caixaimpulse.com/en/home
The CaixaImpulse Call is intended for the financing of projects focused on the valuation and commercialization of the protected or susceptible assets protected by the investigation. Projects must be related to the fields of life sciences, medical sciences and health sciences, specifically in the following fields: Life sciences: biomathematics, cell biology, human biology, biochemistry and […]
The Transcatheter Aortic Valve Implantation (TAVI) is emerging as the most frequent approach to the treatment of aortic stenosis, which is the most frequent valvular disease and in increasing prevalence given population aging.
One of the most frequent drawback of the TAVI procedure is cardiac conduction alterations, which, although not prognostically serious, involve resource consumption with eventual pacemaker implantation in 5-15% of patients. The most frequent conduction disorder (CD), new-onset persistent left bundle branch block occurs in 25% of the procedures and it has been associated with an increased risk of advanced CD requiring permanent pacemaker implantation (PPI) and may induce a reduction in ventricular function.
This multicenter collaborative study published in the American Journal of Cardiology, sought to determine, in patients with persistent left bundle branch block after TAVI, the incidence and factors associated with its reversibility or pacemaker implantation at 1 year of tracing.
In this study the hospitals of Canada, USA, France and Spain have participated. The study has been led by the Quebec Heart and Lung Institute Laval University by Dr. Josep Rodés senior researcher at TAVI. Given the limited caseload of TAVI per center, these network studies are necessary to achieve the necessary sample sizes.
This study is part of a line of research already initiated with the MARE study (J Am Coll Cardiol Cardiovasc Interv 2018; 11: 1495-1505) in which the Marqués de Valdecilla University Hospital also participated and whose research was conducted by Dr. Gabriela Veiga Fernandez.
The study concluded that the new persistent left bundle branch block after TAVI was resolved in one third of the patients a year of follow-up, but no clinical or electrocardiographic variable was associated with recovery. In contrast, a non-sinus rhythm at the start of the study and a longer prolongation in the PR segment were associated with a higher risk of requiring a pacemaker implant within the year after TAVI.
Ref. Late Electrocardiographic Changes in Patients With New-Onset Left Bundle Branch Block Following Transcatheter Aortic Valve Implantation. Faroux L, Muntané-Carol G1, Urena M, Nombela-Franco L, Amat-Santos I, Kleiman N, Munoz-Garcia A, Atienza F, Serra V, Deyell MW, Veiga-Fernandez G, Masson JB, Canadas-Godoy V, Himbert D, Fischer Q, Castrodeza J, Elizaga J, Pascual JF, Webb JG, de la Torre JM, Asmarats L, Pelletier-Beaumont E, Alméndarez M1, Couture T1, Philippon F1, Rodes-Cabau J12. DOI: 10.1016/j.amjcard.2019.11.025
The Transcatheter Aortic Valve Implantation (TAVI) is emerging as the most frequent approach to the treatment of aortic stenosis, which is the most frequent valvular disease and in increasing prevalence given population aging. One of the most frequent drawback of the TAVI procedure is cardiac conduction alterations, which, although not prognostically serious, involve resource consumption […]
